IB Biology HLSkill Set 3 — Maths for BiologyPaper 1, 2 & IACore skill~12 min read
Maths Skills for Biology
Nobody fails Biology because the maths is hard. The sums here are the ones you did at 14. People lose marks because they pick the wrong average, use the wrong percentage formula, or forget what the number is actually telling them about the organism.
📚 What you need to know
You are expected to handle decimals, fractions, percentages, ratios, proportions, frequencies, densities, approximations and reciprocals.
Mean, median and mode are the measures of central tendency — they describe the typical value.
Standard deviation (SD), standard error (SE) and interquartile range (IQR) are measures of dispersion — they describe the spread. SE is always smaller than SD.
Scientific notation (standard form) is written as a × 10n, where a is between 1 and 10.
Rate of change = change in the dependent variable ÷ change in the independent variable.
Percentage change needs a starting value. Percentage difference compares two values, and has a symmetrical version for when there is no baseline.
Discrete data is counted; continuous data is measured and can take any value in a range.
You should be able to choose the right test: chi-squared, t-test, correlation, Simpson’s reciprocal index and the Lincoln index.
The maths you will actually use
Every one of these turns up somewhere in the course. It helps to know where, because then the maths stops feeling random.
Type of number
Where it shows up in Biology
Decimals
Almost every measurement — the length of a bacterial cell, the mass of a seedling
Fractions
Your calculator often gives an answer as a fraction. Find the button that flips it to a decimal before the exam, not during it
Percentages
Percentage change in mass in an osmosis practical, percentage cover in a quadrat
Ratios
Surface area to volume ratio — the one ratio you must be fluent with
Proportions
Scaling a drawing up or down from a micrograph so the shape stays true
Frequencies
Allele frequency in a population, and how it shifts over generations
Densities
Population density in ecology, stomatal density on a leaf
Approximations
Quick estimates, such as checking a magnification answer looks sensible
Reciprocals
Turning a time into a rate: rate = 1 ÷ time taken
The reciprocal trick catches people out. If a colour change takes 50 seconds, the rate is 1/50 = 0.02 s−1. A faster reaction takes less time, so it gets a bigger rate. That is exactly why we flip it — a graph of time looks upside down compared to a graph of rate.
Averages: mean, median and mode
These three all try to answer the same question — “what is a typical value here?” — but they answer it in different ways.
Average
How you find it
What it is good for
Mean
Add up all the values, divide by how many there are
Summing up a whole data set in one number. It uses every value, so every value affects it
Median
Put the values in order and take the middle one
Data with an odd result that would drag the mean off. Half the values sit below it, half above
Mode
The value that appears most often
Categories, where a mean makes no sense — the most common blood group, the most common eye colour
Eight quadrats gave counts between 3 and 7. The mean says 6.7, which describes none of them. The median, 5, describes the field far better.
If a question gives you a data set with one value miles away from the rest, the examiner usually wants you to notice it. Say the mean is affected by the outlier and that the median is more representative here. That one sentence is often the mark.
Spread: how tightly packed is the data?
A mean on its own is only half a story. Two sets of results can have exactly the same mean and still be nothing alike. That is what the measures of dispersion are for.
Report a mean without a spread and you have hidden the difference between these two groups completely.
Measure
What it tells you
Watch out for
Standard deviation (SD)
How far the values sit from the mean on average. Small SD means the results are consistent
You must work out the mean first. Useful for comparing how consistent two data sets are
Standard error (SE)
How far your sample mean is likely to be from the true mean of the whole population
It is about how good your sample is, not how varied the organisms are. SE is always smaller than SD
Interquartile range (IQR)
The difference between the 75th and 25th percentiles — the range of the middle half of the data
Quartiles cut the ordered data into four equal parts. The IQR ignores extreme values completely
🧠
SD or SE?
SD = how Different the individuals are from each other. SE = how Exact your estimate of the mean is. If you sample more organisms, SE shrinks, but SD does not have to.
Scientific notation
Biology jumps between the size of a ribosome and the size of a rainforest, so you need a tidy way to write very big and very small numbers. Scientific notation, also called standard form, does that.
Standard form
a × 10n
a is a number that is at least 1 and less than 10.
n is a whole number. If n is positive, it counts how many times a is multiplied by 10 — the number is big.
If n is negative, it counts how many times a is divided by 10 — the number is small.
Quick check. 0.0000000001 m is 1 × 10−10 m, roughly the width of an atom. 602 000 000 000 000 000 000 000 is 6.02 × 1023, the number of particles in a mole. Same numbers, far less ink.
Approximation and estimation
These two words sound identical and get used loosely, but the exam treats them as different jobs.
Approximation is finding a value close enough to the real one, usually because working it out exactly would be slow or fiddly. You could get the exact answer — you have chosen not to.
Estimation is making an informed judgement when the true value cannot be measured directly. Nobody was there to time it, so you reason from the evidence you do have.
The classic biological estimate is the age of the first cells and of LUCA. No fossil has a date stamped on it, so biologists count mutations and run a molecular clock instead. That is estimation, and it is why those dates are always given as “about”.
Rates of change
A rate tells you how fast something changes. In Biology it is nearly always “how much, per unit of time”.
Average rate of change
rate = change in the dependent variable ÷ change in the independent variable
If you have a table, subtract one row from another. If you have a graph, the rate is the gradient. Both give the same thing, so use whichever the question hands you.
WE 1
Calculate a rate from a table
A respirometer measured the oxygen used by germinating seeds. At 2 minutes, 0.8 cm3 had been used. At 10 minutes, 3.2 cm3 had been used. Calculate the average rate of oxygen uptake. (2 marks)
Step 1: find both changes
change in volume = 3.2 − 0.8 = 2.4 cm3
change in time = 10 − 2 = 8 minStep 2: divide, and keep the units
rate = 2.4 ÷ 8 = 0.30
0.30 cm3 min−1the unit is a giveaway mark — “per minute” comes straight from the bottom of the fraction
Describing trends: proportionality and correlation
Examiners are fussy about these words, so use them precisely.
Term
What it means
Directly proportional
A straight-line relationship: if x doubles, y doubles. As one goes up, so does the other, by the same factor
Inversely proportional
If x doubles, y halves. As one goes up, the other comes down
Positive correlation
The graph slopes upwards: as x increases, y increases. It does not have to be a straight line
Negative correlation
The graph slopes downwards: as x increases, y decreases
Not the same thing. Every directly proportional relationship is a positive correlation, but plenty of positive correlations are not proportional. “Proportional” is a strong claim — only use it for a straight line that heads for the origin.
Percentage change and percentage difference
This is where most of the lost marks live. Both compare two numbers, but they answer different questions, and they use different formulas.
Percentage change
Use this when one value came before the other — a starting mass and a final mass, a count before treatment and after.
Percentage change
(final value − initial value) ÷ initial value × 100
Divide by the initial value, because that is the thing you are comparing against. A negative answer simply means it went down, and you should say so.
Percentage difference
Use this when you are comparing two values that are just… two values. There are two versions, and the question decides which one you need.
Method 1 — relative change
(number A − number B) ÷ number A × 100
Method 2 — symmetrical difference
(number A − number B) ÷ [(number A + number B) ÷ 2] × 100
Method 1 treats A as the baseline, so it answers “how much bigger is B compared with A?”. Method 2 divides by the mean of the two numbers instead, so it does not matter which one you call A. Use it when neither value is a starting point.
The words “increased to”, “after” and “originally” all point at percentage change. Words like “compare” with no before-and-after point at percentage difference.
WE 2
Percentage change in an osmosis practical
A potato cylinder had a mass of 5.20 g. After 30 minutes in a sucrose solution its mass was 4.42 g. Calculate the percentage change in mass. (2 marks)
Step 1: there is a clear starting mass, so use percentage change
change = 4.42 − 5.20 = −0.78 gStep 2: divide by the initial mass and multiply by 100
(−0.78 ÷ 5.20) × 100 = −15.0
−15.0 % (a 15 % loss in mass)keep the minus sign and say what it means — water left the cells, so the solution was more concentrated than the cell sap
WE 3
Symmetrical percentage difference
A student counted stomata on two leaf surfaces. The mean was 12 stomata per mm2 on the upper surface and 68 per mm2 on the lower surface. Calculate the percentage difference between them, to three significant figures. (3 marks)
Step 1: decide on the method
Neither surface is a starting value, so there is no baseline — use the symmetrical formula.
Step 2: find the difference
68 − 12 = 56
Step 3: find the mean of the two values
(68 + 12) ÷ 2 = 40
Step 4: divide and multiply by 100
(56 ÷ 40) × 100 = 140
140 % differencea percentage over 100 is fine here — the gap between the two values is bigger than their average
Discrete and continuous data
Which type you have decides how you graph it and which test you can use, so sort this out early.
Type
What it is
Biological examples
Discrete
Quantitative data made of separate, countable values. You cannot have half of one
Number of woodlice in a sample, number of offspring in a litter
Continuous
Quantitative data from measuring. It can take any value in a range, including decimals
Temperature of an enzyme reaction over time, volume of oxygen released by pondweed
Choosing a statistical test
You will be given the formulas in the exam. What you have to supply is the judgement about which one fits.
Test or index
Use it when you want to…
t-test
Compare the means of two sets of data and decide whether the difference is significant. The data should be continuous, roughly normally distributed, with similar standard deviations
Chi-squared test
Compare observed results with expected results — the outcome of a genetic cross, or whether two species are associated
Correlation test
Find out whether two variables are related, and how strongly
Simpson’s reciprocal index
Measure the biodiversity of a community. It takes in both the number of species (richness) and how many individuals of each (evenness). A higher value means more biodiversity
Lincoln index
Estimate the size of an animal population by capture, mark, release and recapture
Three things push you towards one test rather than another: the size of the sample, whether the data is discrete or continuous, and what the question is actually asking.
💡 Exam tips
Write the formula down first, then substitute. If your arithmetic goes wrong you can still pick up the method mark.
Never round part-way through. Carry the full number on your calculator and round only the final answer.
Give every answer a unit, unless it is a percentage, a ratio or an index value.
If a question says “show your working”, the answer alone will not get full marks even if it is right.
For percentage change, divide by the starting value. For a symmetrical percentage difference, divide by the mean of the two.
Sanity-check the size of your answer. A cell that comes out 3 m wide means a unit slipped somewhere.
⚠ Common mistakes
Dividing by the final value in a percentage change. It is always the initial value on the bottom.
Dropping the minus sign. A loss of mass is a negative percentage change, and the sign carries meaning.
Quoting a mean with no measure of spread. Two very different data sets can share a mean.
Mixing up SD and SE. SD describes the data; SE describes how reliable the mean is. SE is always the smaller of the two.
Calling any upward trend “proportional”. Proportional means a straight line through the origin.
Using the mode for continuous data. If every measured value is different, there is no meaningful mode.
Up next: Units, Symbols & Values — the SI base units, the prefixes from nano to kilo, and the significant figure rules that decide how your answer is written down.
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